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Breaking the Bottleneck: How Mott’s 3D-Printed Impeller is Revolutionizing Perfusion Filtration

In a world where higher throughput and cleaner performance are non-negotiable, traditional filtration methods are starting to hit their limits. At Mott, we’re challenging those limits by rethinking how filters are built — not just in material, but in form.

One of the most promising innovations born from this approach. A 3D-printed metal impeller engineered to solve the toughest challenges in perfusion systems.

Rethinking Filtration from the Inside Out

For years, conventional filters have relied on basic geometries like screens or meshes to get the job done. But in complex systems like bioreactors or continuous processing units, these designs often fall short. They clog easily, degrade under high shear forces, and limit throughput — especially in upstream perfusion applications.

That’s where our new impeller design steps in.

Using advanced metal 3D printing, Mott engineers developed a custom impeller that functions as both a filter and a disperser, enabling a smarter, more durable alternative to traditional filters.

More Than a Filter – A Flow Solution

The new impeller’s design tackles several pain points in a single solution:

  • Continuous, high-density perfusion with lower clogging risk
  • Optimized internal geometry for higher flow and consistent shear forces
  • Enhanced durability, thanks to the use of sintered metal construction
  • Reduced waste through a reusable, easy-to-clean format

The use of a metallic, porous impeller has the potential to improve perfusion processes by enabling higher volumetric throughput,” says Vince Palumbo, Technical Program Manager at Mott.

Better Performance, Smaller Footprint

The 3D-printed impeller isn’t just about solving immediate filtration issues – it also supports broader goals like sustainability and operational efficiency. Because the component is custom-built for each application, it eliminates unnecessary waste, reduces replacement cycles, and supports cleaner, more scalable systems.

It’s a small part with a big impact – one that enables next-generation processes to perform faster, cleaner, and more reliably.

Pushing the Boundaries of What’s Possible

At Mott, we’ve long specialized in the design and manufacturing of engineered porous metal solutions. By integrating additive manufacturing into our process, we’re opening up new opportunities to solve filtration challenges that were once thought to be untouchable.

This is just the beginning.

Want to learn more?

We’re already working with partners across life sciences and energy to tailor these 3D-printed innovations to their systems. If you’re interested in exploring how advanced filtration can support your process, contact our engineering team.

Read the full article in Filtration & Separation Magazine here.